Peptide profile
Myristoyl Pentapeptide-17 (Keratinocyte Growth Factor Fragment)
Myristoyl pentapeptide for hair stimulation
Compare Myristoyl Pentapeptide-17 (Keratinocyte Growth Factor Fragment) with other peptides →Summary
A tiny protein that helps your hair grow.
- Typical dose
- 2-4% concentration 1x daily
- Route
- Topical
- Cycle length
- 3-6 months
- Evidence
- Animal data
Mechanism
How it works
This peptide works like a growth hormone for hair follicles — it tells the cells that produce hair shafts to multiply and stay active longer.
Myristoyl pentapeptide-17 is a fragment of keratinocyte growth factor (KGF) that binds to FGFR2 receptors on keratinocytes and dermal papilla cells.
Reported in research
Benefits
- Helps skin cells that make hair grow faster
- Keeps hair in its growing stage longer
- Makes each hair thicker
- Helps you lose less hair
Context, not a prescription
Dosing
- Typical range
- 2-4% concentration 1x daily (Topical)
- Cycle length
- 3-6 months
Safety
Side effects & contraindications
Possible side effects
- Minimal scalp irritation
- Mild tingling
- Contact dermatitis
Contraindications
- Pregnancy or breastfeeding (limited data)
Research information, not medical advice. Always consult a licensed clinician before considering any peptide.
In depth
Full profile
What it does
Fuller hair, thicker strands, and less hair falling out.
How it works
Think of it like a coach for your hair roots. It tells the cells to make more hair and keep working longer.
It turns on special spots on your hair cells. This helps them grow and stay in the growing stage longer.
What to expect
You can see results in about 3-4 months.
- Weeks 4-8: You lose less hair each day.
- Months 2-3: New hair starts growing in.
- Months 4-6: Hair gets thicker and fuller.
Good to know
- Test a little on your arm before using it on your head
Staying safe
- A little skin itch
- A small tingly feeling
Avoid if you have:
- Moms who are pregnant or breastfeeding (we do not know enough yet)
Mechanism of action
Myristoyl pentapeptide-17 is a fragment of keratinocyte growth factor (KGF) that binds to FGFR2 receptors on keratinocytes and dermal papilla cells.
Activates FGF receptors on hair follicle keratinocytes, promoting proliferation and delaying catagen transition.
Pharmacodynamics
Visible results at 3-4 months.
Increased hair density, thicker strands, reduced shedding.
Timeline
- Weeks 4-8: Reduced daily shedding.
- Months 2-3: New hair growth (vellus to terminal).
- Months 4-6: Increased thickness and density.
Comparisons
- KGF Peptide — effectiveness Emerging, safety Good, cost $$, Easy to use
- Minoxidil — effectiveness Moderate, safety Good, cost $, Easy to use
Adverse effects
Common:
- Minimal scalp irritation
- Mild tingling
Rare:
- Contact dermatitis
Contraindications & risk mitigation
Contraindicated in:
- Pregnancy or breastfeeding (limited data)
- Patch test on forearm before scalp use
Qué hace
Cabello más abundante, hebras más gruesas y menos caída.
Cómo funciona
Piensa en ello como un entrenador para tus raíces capilares. Le indica a las células que produzcan más cabello y que sigan trabajando por más tiempo.
Activa puntos específicos en tus células capilares. Esto ayuda a que crezcan y permanezcan en la etapa de crecimiento por más tiempo.
Qué esperar
Puedes ver resultados en aproximadamente 3-4 meses.
- Semanas 4-8: Pierdes menos cabello cada día.
- Meses 2-3: Comienza a crecer nuevo cabello.
- Meses 4-6: El cabello se vuelve más grueso y abundante.
Bueno saber
- Prueba una pequeña cantidad en el brazo antes de usarlo en la cabeza
Manteniéndose seguro
- Un poco de picazón en la piel
- Una leve sensación de hormigueo
Evitar si tienes:
- Mujeres embarazadas o en lactancia (aún no hay datos suficientes)
Mecanismo de acción
El Myristoyl Pentapeptide-17 es un fragmento del factor de crecimiento de queratinocitos (KGF) que se une a los receptores FGFR2 en queratinocitos y células de la papila dérmica.
Activa los receptores de FGF en los queratinocitos del folículo piloso, promoviendo la proliferación y retrasando la transición a la fase catagen.
Farmacodinamia
Resultados visibles a los 3-4 meses.
Mayor densidad capilar, hebras más gruesas, reducción de la caída.
Cronología
- Semanas 4-8: Reducción de la caída diaria.
- Meses 2-3: Crecimiento de nuevo cabello (de vello a terminal).
- Meses 4-6: Aumento del grosor y la densidad.
Comparaciones
- Péptido KGF — efectividad Emergente, seguridad Buena, costo $$, Fácil de usar
- Minoxidil — efectividad Moderada, seguridad Buena, costo $, Fácil de usar
Efectos adversos
Comunes:
- Irritación mínima del cuero cabelludo
- Hormigueo leve
Raros:
- Dermatitis de contacto
Contraindicaciones y mitigación de riesgos
Contraindicado en:
- Embarazo o lactancia (datos limitados)
- Prueba de parche en el antebrazo antes de usarlo en el cuero cabelludo
Reference data
Specifications
- Route
- Topical
- Cycle length
- 3-6 months
FAQ
Common questions
Is it safe for women with androgenetic alopecia?
Yes, it does not affect hormones and is safe for both men and women.
Can it regrow a receding hairline?
Partial regrowth possible; most effective for crown thinning.
What is the evidence level?
This compound is classified as Animal data. Most data comes from preclinical animal studies. Human clinical trial evidence is limited or absent.
Research
Research & sources
Current evidence for Myristoyl Pentapeptide-17 (Keratinocyte Growth Factor Fragment) is rated as Animal data. Research is based primarily on animal models.
- 1. KGF peptide in hair (2012) — DOI:10.1111/j.1346-8138.2012.01603.x
- 2. Peptide hair growth review (2020) — DOI:10.1111/jocd.13287
- 3. KGF peptide in hair (2012)
- 4. Peptide hair growth review (2020)